Carfilzomib

Carfilzomib (marketed under the trade name Kyprolis, developed by Onyx Pharmaceuticals) is an anti-cancer drug acting as a selective proteasome inhibitor.

CAS# 868540-17-4

Carfilzomib

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2-Isocyanatopyridine

2-Isocyanato-pyridine is an intermediate used to prepare benzothiazoles as analogs of BMS-243117 as potent and selective p56lck inhibitors. It is also used to synthesize ergolines as antagonists of chemokine receptor CXCR3. CAS# 4737-19-3
2-Isocyanatopyridine

 

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psychostimulant—-CDP-choline

Citicoline (INN), also known as cytidine diphosphate-choline (CDP-Choline) or cytidine 5′-diphosphocholine is a psychostimulant/nootropic. It is an intermediate in the generation of phosphatidylcholine from choline.

CAS# 987-78-0

CDP-choline

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a 38 percent reduction in the risk of death—Jardiance(Eli Lilly)

Eli Lilly today announced a new analysis of the EMPA-REG OUTCOME trial that Jardiance (empagliflozin) tablets can reduce the risk of cardiovascular death in patients with type 2 diabetes and cardiovascular disease.

Jardiance is the first and only oral drug to be used to reduce the risk of cardiovascular death in patients with type 2 diabetes and cardiovascular disease and has the potential to change this status.

reference:

[1] Eli Lilly (LLY) Release: Jardiance (Empagliflozin) Tablets Reduced Risk Of Cardiovascular Death In People With Type 2 Diabetes And Established Cardiovascular Disease Independent Of Background Blood Sugar Control

 

phytoremediation—using poplar trees to soak up pollutants(TCE)

TCE contaminates the soil or water of more than 1,000 Superfund sites around the U.S. Current methods to remove it is too expensive to  implement. Now researchers have developed a much cheaper approach. This method uses plants to soak up contaminants from oil and groundwater. Moreover, introducing symbiotic, pollutant-destroying bacteria to these poplar trees has exhibited even better results. Sounds amazing!!! (visit the website of c&en to learn more details)

Daptomycin CAS# 103060-53-3

Product Name: Daptomycin

CAS# 103060-53-3

MOA: Cell membrane depolarizing agents Cell membrane inhibitors Lipopeptide antibiotic

Indication: Complicated Skin and Skin Structure Infections ( cSSSI) Staphylococcus aureus bloodstream infections

Structure:

Daptomycin CAS#103060-53-3

Price and lead time information, please feel free to contact us at  Freya_Wang@accelpharmtech.com .